Dallocchio Roberto Nico

Dallocchio Roberto Nico

    • Technicians
  • 11 Febbraio 2015
  • 1204


Profile: Technician

Office location: Sassari

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Work phone #: 0792841213

Lab phone #: 0792841135

Mobile: 3204639936


Roberto Dallocchio, born in Sassari in 1962, carries out its activities as a technician in the National Research Council (CNR) since 1984 Diplomato in chemistry, in time has acquired a great experience in computer programming, and in management of computer networks.

He mainly deals with computational modeling of biomolecules. These calculations include the use of techniques of molecular mechanics, quantum chemistry, docking, virtual screening and molecular dynamics.

His experience includes the following software: Sybyl, Autodock, Gaussian, Amber.

Has founded in 2001 the molecular modelling group of the ICB Institute of Sassari.

Is coauthor of numerous publications in international journals of chemistry / biology.

His computer experience led him to play different positions in the field of computer networks, such as the design of infrastructure networks of CNR in Sardinia, the management and programming of devices, such as routers, switches and firewalls (mainly Cisco devices ) Currently manages the Computing Center of the CNR Research Area of Sassari, where he specialized in the management of computing servers, virtualization, NAS storage , and  application oriented  to web (HTML, Javascript, PHP, etc.) He gained experience in various programming languages, including C, C++, Pascal, and in the programming world of relational databases (MSQL,MySQL and PosgreSQL)


Skills and expertise:

  • Docking studies
  • Virtual Screening
  • Molecular graphics
  • Molecular Modeling
  • Molecular Dynamics
  • Computer Programming


  • Computational Chemistry
  • Medicinal Chemistry
  • Inorganic Chemistry
  • Spectroscopy
  • Computer Networks

Major publications

  1. Natural and Natural-like Phenolic Inhibitors of Type B Trichotecene in Vitro Production by the Wheat (triticum sp.) Pathogen Fusarium culmorum -  Giovanna Pani, Barbara Scherm, Emanuela Azara, Virgilio Balmas, Zahra Jajanshiri, Paola Carta, Davide Fabbri, Maria Antonietta dettori, Angela Fadda, Alessandro dessì, Roberto Dallocchio, Quirico Migheli and Giovanna Delogu - Journal of Agricultural and Food Chemistry, 2014, 62, 4969-4978 -DOI: dx.doi.org/10.1021/jf500647h
  2. Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease - A. Stevaert, R. Dallocchio, A. Dessì, N. Pala, D. Rogolino, M. Sechi, L. Naesens - Journal of Virology, 2013, 87, 19, 10524-10538 - DOI: 10.1128/JVI.00832-13
  3. Virtual Screening-Driven Identification of Human Carbonic Anhydrase Inhibitors incorporating an Original, New Pharmacophore - Nicolino Pala,a Roberto Dallocchio,b Alessandro Dessì,b Andrea Brancale,c Fabrizio Carta,d Simone Ihm,a Alfonso Maresca,d Mario Sechi,a,* Claudiu T. Supurand,* - Bioorganic & Medicinal Chemistry Letters, 2011, 21, 2515-2520 DOI: 0.1016/j.bmcl.2011.02.059
  4. Design and Synthesis of Novel Polycycles Based on the 3H- pyrrolo/6,7- dihydropyrido[1,2-a]indole scaffold as Templates for Pharmaceutical Development - Derudas Marco,Pala Nicolino,Sanna Vanna,Dallocchio Roberto,Dessì Alessandro,Roggio Anna Maria,Sechi Mario - Journal of Heterocyclic Chemistry , 2011, 48, 1161-1168 - DOI: 10.1002/jhet.710
  5. DNA Binders: 2. Molecular Recognition of DNA by 2,3,6,7-tetrahydro-1Hpyrrolo[1,2-a]indole-1,8(5H)-dione bis(4,5-dihydro-1H-imidazol-2-yl-hydrazone) as a Prototype of “Two-Armed” Intercalating Agents - R.Dallocchio, A. Dessì, V. Sanna, N. Pala, I. Campesi, G. Paglietti, M. Sechi - Letters in Drug Design & Discovery, 2009, 6, 246-251 - DOI: 10.2174/157018009788452537
  6. Design, synthesis, molecular modeling, and anti-HIV-1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes - M. Sechi, F. Carta, L. Sannia, R. Dallocchio, A. Dessì, R. Al-Safi, N. Neamati - Antiviral Research, 2009, 81, 267–276 DOI: 10.1016/j.antiviral.2008.12.010
  7. DNA Binders: 1. Evaluation of DNA-Interactive Ability, Design, and Synthesis of Novel Intercalating Agents - M. Sechi, M. Derudas, R. Dallocchio, A. Dessì, A. Cosseddu, G. Paglietti  - Letters in Drug Design & Discovery, 2009, 6, 56-62 - DOI: 10.2174/157018009787158472 
  8. Design and Synthesis of Bis-amide and Hydrazide-containing Derivatives of Malonic Acid as Potential HIV-1 Integrase Inhibitors -M. Sechi, U. Azzena, M.P. Delussu, R. Dallocchio, A. Dessì, A. Cosseddu, N. Pala and N. Neamati - Molecules 2008, 13, 2442-2461- DOI: 10.3390/molecules13102442
  9. Design of Novel Bioisosteres of Β-diketoacid inhibitors of HIV-1 Integrase Inhibitors - M. Sechi, L. Sannia, F. Carta, M. Palomba, R. Dallocchio, A. Dessi, M. Derudas, Z. Zawahir and N. Neamati - Antiviral Chemistry & Chemotherapy ,16:41-61 (2005)
  10. Design and Synthesis of Novel Indole β-Diketo Acid Derivatives as HIV-1 Integrase Inhibitors - M. Sechi, M. Derudas, R. Dallocchio, A. Dessi, A. Bacchi, L. Sannia, F. Carta, M. Palomba, O. Ragab, C. Chan, R. Shoemaker, S. Sei, R. Dayam and N. Neamati - J. Med. Chem, 47, 5298-5310 (2004) - DOI: 10.1021/jm049944f


Docking, Molecular Dynamics, Virtual Screening, Anti HIV, Anti Virali